Influence of pressure and velocity gradients during atomization on deformation and viability of mesenchymal stem cells

  Deformation and viability of mesenchymal stem cells in a picture WSA

In context of regenerative medicine different methods could be used for applying of stem cells. Especially a novel approach could make a significant contribution for improved healing of until now remediless diseases: the atomization of cell-solutions (cell-spraying). However, atomization is characterized by high shearing and extensional flows, whose effects on cell viability and cell behavior are hardly understood. Therefore, this project aims at a better understanding of cell behavior during and after spray application.

 

Project Details

Project Manager

Project Duration

05/2018 - 10/2019

 

Funded by

DFG Zukunftskonzept II, RWTH Aachen Start-Up

Partner

Dr. Lena Thiebes, AME-Helmholtz Institut für Biomedizinische Technik, Biohybrid & Medical Textiles, BioTex

 

Infrastructure

  • Mikroskopie
    • Messzelle für Stammzellen in Dehnströmungen